Definition:The strict +2°C to +8°C temperature range required for most vaccines, biologics, and temperature-sensitive pharmaceuticals per GDP requirements.
Why So Strict::
- Below +2°C: Product may freeze (damage)
- Above +8°C: Product potency may degrade
- Temperature excursions may render product ineffective or unsafe
Regulatory Context:: WHO GDP, SAHPRA requirements, mandatory for pharmaceutical distribution.
Related Terms:: GDP, SAHPRA, Temperature Excursion, Qualified Transport
Find Services:: GDP-compliant pharmaceutical cold chain providers